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J Li, H Chai, Y Li, X Chai, Y Zhao, Y Zhao, T Tao and X Xiang
Abstract
Amoxicillin is a commonly used antibiotic which has a short half-life in human. The frequent administration of amoxicillin is often required to keep the plasma drug level in an effective range. The short dosing interval of amoxicillin could also cause some side effects and drug resistance, and impair its therapeutic efficacy and patients' compliance. Therefore, a three-pulse release tablet of amoxicillin is desired to generate sustained release in vivo, and thus to avoid the above mentioned disadvantages.
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Concepts
Effect, In vivo, First-person shooter, Antibiotic resistance, Effectiveness, Efficacy, Pharmacology
MeSH headings
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