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KL Whitcroft, C Merkonidis, M Cuevas, A Haehner, C Philpott and T Hummel
Abstract
Calcium plays an integral role in olfactory signal transduction, including feedback inhibition. Sodium citrate acts as a calcium sequestrant and when applied intranasally, reduces free calcium available for feedback inhibition, which should theoretically improve olfaction. We aimed to investigate the utility of intranasal sodium citrate in improving the olfactory function of hyposmic patients, by performing this prospective placebo controlled, single-blind trial.
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Concepts
Calcium, Better, Sodium citrate, Improve, Olfaction
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