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N Derakhshan and M Kazemi
Abstract
Psoriasis is a common skin disorder characterized by hyper proliferation of keratinocytes. Although the exact pathophysiology of psoriasis is not entirely understood, immune system and its interaction with nervous system has been postulated and investigated as the underlying mechanism. The interaction between these two systems through cholinergic anti-inflammatory pathway and also endocannabinoid system, may suggest cannabinoids as potential addition to anti-psoriatic armamentarium.
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Concepts
Immune system, Dopamine, Parasympathetic nervous system, Neurotransmitter, Nervous system, Cannabinoid
MeSH headings
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