The Long-term Efficacy and Safety of Fecal Microbiota Transplant for Recurrent, Severe, and Complicated Clostridium difficile Infection in 146 Elderly Individuals
Journal of clinical gastroenterology | 10 Sep 2015
M Agrawal, OC Aroniadis, LJ Brandt, C Kelly, S Freeman, C Surawicz, E Broussard, N Stollman, A Giovanelli, B Smith, E Yen, A Trivedi, L Hubble, D Kao, T Borody, S Finlayson, A Ray and R Smith
Clostridium difficile infection (CDI) in the elderly has a higher prevalence, greater morbidity and mortality, and lower response to conventional treatment than the general population. Fecal microbiota transplant (FMT) is highly effective therapy for CDI but has not been studied specifically in the elderly. This study aims to determine the long-term efficacy and safety of FMT for recurrent (RCDI), severe (SCDI), and complicated (CCDI) CDI in elderly patients.
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