Maternal gestational vitamin D supplementation and offspring bone health (MAVIDOS): a multicentre, double-blind, randomised placebo-controlled trial
OPEN The lancet. Diabetes & endocrinology | 6 Mar 2016
C Cooper, NC Harvey, NJ Bishop, S Kennedy, AT Papageorghiou, I Schoenmakers, R Fraser, SV Gandhi, A Carr, S D'Angelo, SR Crozier, RJ Moon, NK Arden, EM Dennison, KM Godfrey, HM Inskip, A Prentice, MZ Mughal, R Eastell, DM Reid and MK Javaid
Maternal vitamin D status has been associated with bone mass of offspring in many, but not all, observational studies. However, maternal vitamin D repletion during pregnancy has not yet been proven to improve offspring bone mass in a randomised controlled trial. We aimed to assess whether neonates born to mothers supplemented with vitamin D during pregnancy have greater whole-body bone mineral content (BMC) at birth than those of mothers who had not received supplementation.
* Data courtesy of Altmetric.com