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Establishing a Framework - Does Testosterone Supplementation Help Older Men?

OPEN The New England journal of medicine | 18 Feb 2016

ES Orwoll
Abstract
Aging is variably but inevitably accompanied by declines in health; concomitantly, in men, circulating sex-steroid levels fall with age.(1) To what extent these two processes are causally linked and whether testosterone therapy can prevent or ameliorate important age-related problems have been major issues in men’s health. In 2003, a committee assembled by the Institute of Medicine (IOM) found a paucity of randomized, placebo-controlled clinical trials involving older men and noted a lack of definite evidence that testosterone therapy conferred benefits.(2) The committee recommended that clinical trials be initiated, first to evaluate the efficacy of testosterone supplementation in older men and . . .
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Concepts
Placebo, Randomized controlled trial, Avicenna, The Canon of Medicine, Death, Clinical trial, Health care, Medicine
MeSH headings
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