Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis.
OPEN PloS one | 9 Aug 2012
SZ Lin, WT Wei, H Chen, KJ Chen, HF Tong, ZH Wang, ZL Ni, HB Liu, HC Guo and DL Liu
Emodin has been showed to induce apoptosis of pancreatic cancer cells and inhibit tumor growth in our previous studies. This study was designed to investigate whether emodin could inhibit the angiogenesis of pancreatic cancer tissues and its mechanism.
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