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S Sood, IJ Gallagher, K Lunnon, E Rullman, A Keohane, H Crossland, BE Phillips, T Cederholm, T Jensen, LJ van Loon, L Lannfelt, WE Kraus, PJ Atherton, R Howard, T Gustafsson, A Hodges and JA Timmons
Abstract
Diagnostics of the human ageing process may help predict future healthcare needs or guide preventative measures for tackling diseases of older age. We take a transcriptomics approach to build the first reproducible multi-tissue RNA expression signature by gene-chip profiling tissue from sedentary normal subjects who reached 65 years of age in good health.
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Concepts
Medical terms, Genetics, Ageing, Old age, Death, Senescence, Medicine, Health
MeSH headings
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