SciCombinator

Discover the most talked about and latest scientific content & concepts.

MJ Ison, R Quian Quiroga and I Fried
Abstract
The creation of memories about real-life episodes requires rapid neuronal changes that may appear after a single occurrence of an event. How is such demand met by neurons in the medial temporal lobe (MTL), which plays a fundamental role in episodic memory formation? We recorded the activity of MTL neurons in neurosurgical patients while they learned new associations. Pairs of unrelated pictures, one of a person and another of a place, were used to construct a meaningful association modeling the episodic memory of meeting a person in a particular place. We found that a large proportion of responsive MTL neurons expanded their selectivity to encode these specific associations within a few trials: cells initially responsive to one picture started firing to the associated one but not to others. Our results provide a plausible neural substrate for the inception of associations, which are crucial for the formation of episodic memories.
Tweets*
144
Facebook likes*
9
Reddit*
2
News coverage*
23
Blogs*
8
SC clicks
0
Concepts
Episodic memory, Human brain, Brain, Nervous system, Neuron, Cerebral cortex, Memory, Hippocampus
MeSH headings
-
comments powered by Disqus

* Data courtesy of Altmetric.com