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Persistence of Ebola Virus in Ocular Fluid during Convalescence

OPEN The New England journal of medicine | 8 May 2015

JB Varkey, JG Shantha, I Crozier, CS Kraft, GM Lyon, AK Mehta, G Kumar, JR Smith, MH Kainulainen, S Whitmer, U Ströher, TM Uyeki, BS Ribner and S Yeh
Abstract
Among the survivors of Ebola virus disease (EVD), complications that include uveitis can develop during convalescence, although the incidence and pathogenesis of EVD-associated uveitis are unknown. We describe a patient who recovered from EVD and was subsequently found to have severe unilateral uveitis during convalescence. Viable Zaire ebolavirus (EBOV) was detected in aqueous humor 14 weeks after the onset of EVD and 9 weeks after the clearance of viremia.
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Concepts
Microbiology, Ebola, Viral hemorrhagic fever, Incubation period
MeSH headings
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