Impact of Preoperative Left Ventricular Ejection Fraction on Long-Term Survival After Aortic Valve Replacement for Aortic Stenosis
Circulation. Cardiovascular quality and outcomes | 10 Jan 2013
JB Goldberg, JP Desimone, RS Kramer, AW Discipio, L Russo, LJ Dacey, BJ Leavitt, RE Helm, YR Baribeau, G Sardella, RA Clough, SD Surgenor, MJ Sorensen, CS Ross, EM Olmstead, TA Mackenzie, DJ Malenka and DS Likosky
BACKGROUND: =0.003). Patients with preserved EF had significantly improved 6-month and 8-year survival compared with their reduced EF counterparts.Conclusions-Survival after AVR or AVR+coronary artery bypass grafting was most favorable among patients with preoperative preserved EF. However, patients with mild to moderately depressed EF experienced a substantial survival benefit compared with the natural history of medically treated patients. Furthermore, minor reductions of EF carried equivalent increased risk to those with more compromised function suggesting patients are best served when an AVR is performed before even minor reductions in myocardial function.
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