Initial Experience Using 99mTc-MIBI SPECT/CT for the Differentiation of Oncocytoma From Renal Cell Carcinoma
OPEN Clinical nuclear medicine | 22 Jan 2015
SP Rowe, MA Gorin, J Gordetsky, MW Ball, PM Pierorazio, T Higuchi, JI Epstein, ME Allaf and MS Javadi
The differentiation of oncocytoma from renal cell carcinoma (RCC) remains a challenge with currently available cross-sectional imaging techniques. As a result, a large number of patients harboring a benign oncocytoma undergo unnecessary surgical resection. In this study, we explored the utility of Tc-MIBI SPECT/CT for the differentiation of these tumors based on the hypothesis that the large number of mitochondria in oncocytomas would lead to increased Tc-MIBI uptake.
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