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Therapeutic dose monitoring of mycophenolate mofetil in dermatologic diseases

Journal of the American Academy of Dermatology | 14 Aug 2012

O Sokumbi, RA El-Azhary and LJ Langman
Abstract
Mycophenolate mofetil (MMF) is used for prevention of allograft rejection in transplantation medicine. In dermatology it is used as a corticosteroid-sparing agent. The pharmacokinetics of MMF are known to vary by individual. Therapeutic dose monitoring of mycophenolic acid (MPA), the active metabolite of MMF, is used as a guide in transplantation medicine, but limited data exist on the benefit of measuring MPA levels in the management of dermatologic disease.
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Concepts
Cyclophosphamide, Dermatology, Disease, Organ transplant, Pharmacology, Medicine, Mycophenolate mofetil, Mycophenolic acid
MeSH headings
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