OPEN BMC medicine | 17 Oct 2014
K Aleksandrova, T Pischon, M Jenab, H Bueno-de-Mesquita, V Fedirko, T Norat, D Romaguera, S Knüppel, MC Boutron-Ruault, L Dossus, L Dartois, R Kaaks, K Li, A Tjønneland, K Overvad, J Quirós, G Buckland, M Sánchez, M Dorronsoro, MD Chirlaque, A Barricarte, KT Khaw, NJ Wareham, KE Bradbury, A Trichopoulou, P Lagiou, D Trichopoulos, D Palli, V Krogh, R Tumino, A Naccarati, S Panico, PD Siersema, P Peeters, I Ljuslinder, I Johansson, U Ericson, B Ohlsson, E Weiderpass, G Skeie, K Borch, S Rinaldi, I Romieu, J Kong, MJ Gunter, HA Ward, E Riboli and H Boeing
Excess body weight, physical activity, smoking, alcohol consumption and certain dietary factors are individually related to colorectal cancer (CRC) risk; however, little is known about their joint effects. The aim of this study was to develop a healthy lifestyle index (HLI) composed of five potentially modifiable lifestyle factors - healthy weight, physical activity, non-smoking, limited alcohol consumption and a healthy diet, and to explore the association of this index with CRC incidence using data collected within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
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