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Neurodevelopmental outcomes in the early CPAP and pulse oximetry trial

The New England journal of medicine | 28 Dec 2012

YE Vaucher, M Peralta-Carcelen, NN Finer, WA Carlo, MG Gantz, MC Walsh, AR Laptook, BA Yoder, RG Faix, A Das, K Schibler, W Rich, NS Newman, BR Vohr, K Yolton, RJ Heyne, DE Wilson-Costello, PW Evans, RF Goldstein, MJ Acarregui, I Adams-Chapman, A Pappas, SR Hintz, B Poindexter, AM Dusick, EC McGowan, RA Ehrenkranz, A Bodnar, CR Bauer, J Fuller, TM O'Shea, GJ Myers and RD Higgins
Abstract
Previous results from our trial of early treatment with continuous positive airway pressure (CPAP) versus early surfactant treatment in infants showed no significant difference in the outcome of death or bronchopulmonary dysplasia. A lower (vs. higher) target range of oxygen saturation was associated with a lower rate of severe retinopathy but higher mortality. We now report longer-term results from our prespecified hypotheses.
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Concepts
Bronchopulmonary dysplasia, Outcome, Cardiology, Pulse oximeter, Oxygen saturation, Pulse oximetry, Oxygen sensor
MeSH headings
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