SciCombinator

Discover the most talked about and latest scientific content & concepts.

Brucellosis among Hospitalized Febrile Patients in Northern Tanzania

OPEN The American journal of tropical medicine and hygiene | 24 Oct 2012

AJ Bouley, HM Biggs, RA Stoddard, AB Morrissey, JA Bartlett, IA Afwamba, VP Maro, GD Kinabo, W Saganda, S Cleaveland and JA Crump
Abstract
Abstract. Acute and convalescent serum samples were collected from febrile inpatients identified at two hospitals in Moshi, Tanzania. Confirmed brucellosis was defined as a positive blood culture or a ≥ 4-fold increase in microagglutination test titer, and probable brucellosis was defined as a single reciprocal titer ≥ 160. Among 870 participants enrolled in the study, 455 (52.3%) had paired sera available. Of these, 16 (3.5%) met criteria for confirmed brucellosis. Of 830 participants with ≥ 1 serum sample, 4 (0.5%) met criteria for probable brucellosis. Brucellosis was associated with increased median age (P = 0.024), leukopenia (odds ratio [OR] 7.8, P = 0.005), thrombocytopenia (OR 3.9, P = 0.018), and evidence of other zoonoses (OR 3.2, P = 0.026). Brucellosis was never diagnosed clinically, and although all participants with brucellosis received antibacterials or antimalarials in the hospital, no participant received standard brucellosis treatment. Brucellosis is an underdiagnosed and untreated cause of febrile disease among hospitalized adult and pediatric patients in northern Tanzania.
Tweets*
0
Facebook likes*
0
Reddit*
0
News coverage*
0
Blogs*
0
SC clicks
1
Concepts
Received Pronunciation, Participation, Blood culture, Physician, Blood type, Fever, Brucellosis, Hospital
MeSH headings
-
comments powered by Disqus

* Data courtesy of Altmetric.com