Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 17 Mar 2012
BJ Cowling, VJ Fang, H Nishiura, KH Chan, S Ng, DK Ip, SS Chiu, GM Leung and JS Peiris
We randomized 115 children to trivalent inactivated influenza vaccine (TIV) or placebo. Over the following 9 months, TIV recipients had an increased risk of virologically-confirmed non-influenza infections (relative risk: 4.40; 95% confidence interval: 1.31-14.8). Being protected against influenza, TIV recipients may lack temporary non-specific immunity that protected against other respiratory viruses.
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- Avian influenza, Innate immune system, English-language films, Immune system, Influenza vaccine, Vaccination, Influenza, Virus
- MeSH headings
- Adolescent, Child, Female, Humans, Immunosuppression, Incidence, Influenza Vaccines, Male, Placebos, Respiratory Tract Infections, Risk Assessment, Vaccines, Inactivated, Virus Diseases
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