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Efficacy of ustekinumab in refractary palmoplantar pustular psoriasis.

The British journal of dermatology | 6 Dec 2012

C Morales-MĂșnera, E Vilarrasa and L Puig
Abstract
Palmoplantar pustulosis is characterized by sterile pustules with hyperkeratosis, erythema, scaling, and fissuring on the palms and soles.(1) It has been reported to be more frequent in middle-aged women, smokers, and diabetic patients(2) , and it is increasingly reported as a paradoxical reaction to antitumor necrosis factor alpha (anti-TNF) biological agents.(3, 4.) It can present itself alone (PPP), or in association with psoriasis vulgaris (palmoplantar pustular psoriasis, PPPP).
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Concepts
Ultraviolet, Psoriatic arthritis, Etanercept, Adalimumab, Ustekinumab, Pustulosis palmaris et plantaris, Tumor necrosis factor-alpha, Psoriasis
MeSH headings
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